Synthetic cannabinoids: Epidemiology, pharmacodynamics, and clinical implications
نویسندگان
چکیده
منابع مشابه
Clinical Pharmacodynamics of Cannabinoids
Our knowledge of the pharmacodynamics of cannabinoids, that is, “the study of the biochemical and physiologic effects of drugs and their mechanisms of action” (The Merck Manual), has considerably increased within the past decade due to the detection of an endogenous cannabinoid system with specific receptors and their endogenous ligands. THC (D9-tetrahydrocannabinol), the main source of the pha...
متن کاملPharmacokinetics and pharmacodynamics of cannabinoids.
Delta(9)-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects caused by the consumption of cannabis, both the marijuana-like action and the medicinal benefits of the plant. However, its acid metabolite THC-COOH, the non-psychotropic cannabidiol (CBD), several cannabinoid analogues and newly discovered modulators of the endogenous cannabinoid system are also promising can...
متن کاملSynthetic cannabinoids
Use of cannabinoids is increasing at an alarming rate. Their easy availability, cheapness, perceptive legality and difficulty in detecting its presence with standard urine toxicologic tests, and similar factors probably contribute to the increased use, and popularity of synthetic cannabinoids. Although laws, and regulations concerning auditing of these substances have been implemented in many c...
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Echinocandins have made a significant impact in the treatment of select invasive fungal infections, most notably invasive candidiasis and aspergillosis. However, treatment outcomes for such infections are still less than optimal, prompting an examination of dosing and administration techniques in an attempt to exploit known pharmacodynamic properties and improve outcomes. Echinocandins generall...
متن کاملSynthetic cannabinoids and renal injury
Dear Editor; I think that review article entitled “Synthetic Cannabinoids” written by Bilici, and published in Vol 12, No.2 pp. 121–6 of your periodical conveys importance in that it emphasizes the awareness concerning a clinical condition whose incidence is increasing as a current, and potential dangerous addiction [1]. Unfortunately, rapidly increasing addiction to narcotics, and synthetic il...
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ژورنال
عنوان ژورنال: Drug and Alcohol Dependence
سال: 2014
ISSN: 0376-8716
DOI: 10.1016/j.drugalcdep.2014.08.005